Molecular Formula | C3H4Cl2F2O |
Molar Mass | 164.97 |
Density | 1.4262 |
Melting Point | -36°C |
Boling Point | 103 °C |
Flash Point | 37°C |
Water Solubility | Miscible with alcohol, acetone, chloroform, ether, fixed oils and benzene. Immiscible with water. |
Exposure Limit | No exposure limit is set. Based on comparison with related compounds, a TLV-TWAof 675 mg/m3 (100 ppm) is recommended. |
Merck | 14,5994 |
BRN | 1737766 |
Storage Condition | -70°C |
Stability | Stability |
Refractive Index | 1.386 |
MDL | MFCD00040144 |
Physical and Chemical Properties | Colorless and easy-to-flow transparent liquid. Melting point -35 ℃, boiling point 105 ℃,(13.3kPa), relative density (20/4 ℃)1.4262, refractive index (nD20)1.3861. It has a fruit scent. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 10 - Flammable |
Safety Description | S23 - Do not breathe vapour. S24/25 - Avoid contact with skin and eyes. |
UN IDs | 3271 |
RTECS | KN7820000 |
HS Code | 2909191800 |
Hazard Note | Irritant |
Hazard Class | 3 |
Packing Group | III |
Toxicity | One of the most potent of the inhalational anesthetics, having a very high blood-gas partition coefficient and low vapor pressure at room temperature. Methoxyflurane is metabolized to a great extent (about 50-70%) in the liver and, as a consequence, there may be release of high concentrations of fluoride, sufficient to exceed the threshold for renal damage. Its use for sustained anesthesia is limited because of this renal toxicity and was discontinued around 1980. |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | is a newer general inhalation anesthetic. Among the known inhaled anesthetics, the general anesthesia efficacy is the strongest, and there is a significant muscle relaxant effect. Currently, it is mostly used for general anesthesia. |
production method | 1,2,-difluoro -1,1,2, 2-tetrachloroethane is rearranged into 1, 1-difluoro-1, 2,2, 2-tetrachloroethane, and then 1 molecule of CL2 is removed, and then added with methanol to obtain methoxyflurane. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |